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April 1, 2026Open Access

Instrumentation and biological applications of high-resolution frequency modulation atomic force microscopy in liquid

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Authors

TFTakeshi FukumaKanazawa University剛福剛士 福間

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Implication

Review summarizes advances in frequency modulation atomic force microscopy for imaging biological materials in liquid, revealing novel insights.

Key Points

  • This review aims to summarize advancements in frequency modulation atomic force microscopy and its biological applications in liquid environments.
  • Review of recent technological progress in FM-AFM instrumentation.
  • Discussion of applications in biology and electrochemistry.
  • Comparison of FM-AFM with other imaging techniques.
  • FM-AFM has been successfully adapted for imaging in liquid environments.
  • The technique provides novel information about biological materials not accessible through other methods.
  • Applications span various fields, enhancing our understanding of biological systems.

Cite This Study

Fukuma et al. (2008) studied this question.

synapsesocial.com/papers/69cd7a6f5652765b073a7884https://doi.org/10.24517/00008297
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Improvements in fundamental performance of liquid-environment atomic force microscopy with true atomic resolution2015
  2. 2Atomic-resolution imaging in liquid by frequency modulation atomic force microscopy using small cantilevers with megahertz-order resonance frequencies2012
  3. 3Progress of AFM single-cell and single-molecule morphology imaging2013 · 21 citations
  4. 4Non-Contact Mechanics of Soft and Liquid Interfaces by Hydrodynamic Confinement Using a Frequency-Modulated AFM2026
  5. 5High-speed atomic force microscopy2012