This review discusses the creation and applications of artificial zinc finger proteins, indicating their potential in therapy.
Zinc finger proteins are abundant in the human proteome and are involved in various functions. Given the biological importance of zinc finger proteins, many artificial zinc finger proteins have been created to improve their function and biological applications. Here, we review previous studies on the redesign and application of artificial zinc finger proteins, focusing on our experimental results. We also discuss the potential biological applications of artificial zinc finger proteins. This review will provide relevant information to researchers working in or interested in the field of engineered zinc finger proteins, which may provide new therapeutic approaches to various diseases.
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Negi et al. (2023) studied this question.
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