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The aim is to investigate the interconversion of lecithin and cephalin in the animal body, focusing on its physiological basis.

April 1, 2026Open Access

Studies on the Interconversion Between Lecithin and Cephalin in Animal Body.

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Studies demonstrate the conversion of cephalin to lecithin in the liver and viscera, suggesting significant physiological processes.

The aim is to investigate the interconversion of lecithin and cephalin in the animal body, focusing on its physiological basis.
Prepared P32-labeled lecithin and cephalin from rat liver phospholipids using chromatography.
Administered labeled phospholipids intravenously and analyzed tissues at intervals from 2 to 18 hours post-administration.
Employed Marinetti's and Dawson's methods to analyze phospholipids and paper chromatography for non-lipid phosphorus compounds.
Conversion of cephalin to lecithin occurs physiologically in the liver and other viscera.
No reverse conversion from lecithin to cephalin was observed.
Lecithin in blood plasma phospholipids appears to derive from viscera, particularly the liver, while plasma cephalin may originate from peripheral tissues.

Tadashi et al. (1965) studied this question.

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