Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
April 1, 2026Japanese Journal of RadiologyOpen Access

Lesion conspicuity assessment of prone 40-keV virtual monoenergetic imaging in arterial-phase photon-counting CT for breast cancer: a retrospective comparison with DCE-MRI

View Full Paper
Ask AI
Bookmark
Share

Authors

YKYusuke KawasakiMNMaika NakajimaKYKota Yokoyama

Discussion

Loading...

Member takes

Overview

Retrospective comparison reveals 40-keV virtual monoenergetic imaging enhances lesion visibility in breast cancer, suggesting potential as an accessible alternative to DCE-MRI.

Key Points

  • The research aims to compare lesion visibility between photon-counting detector CT and dynamic contrast-enhanced MRI for breast cancer assessment.
  • Conducted a retrospective feasibility study at a single center.
  • Included 22 women with confirmed primary breast cancer undergoing both PCD-CT and DCE-MRI.
  • Evaluated 40- and 70-keV virtual monoenergetic images (VMI) alongside DCE-T1WI using three independent readers.
  • 40-keV VMI showed the highest lesion conspicuity compared to 70-keV VMI and DCE-T1WI.
  • Absolute size error for 40-keV VMI was larger than DCE-T1WI, but not statistically significant.
  • Detection rates differed among modalities, with no significant pairwise differences.
  • 40-keV VMI had higher background parenchymal enhancement and perceived noise, requiring longer reading times.

Cite This Study

Kawasaki et al. (2026) studied this question.

synapsesocial.com/papers/69cd7aa45652765b073a7feehttps://doi.org/10.1007/s11604-026-01979-7
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Phantom evaluation of spectral performance in photon‐counting CT for breast cancer imaging2026
  2. 2Prone Photon-counting Computed Tomography With Iodine Mapping for Differentiating Breast Masses: A Prospective Study2025
  3. 3Segmented Coronal Breast Maximum Intensity Projection Images Derived From Contrast-Enhanced Chest Computed Tomography: A Proof-of-Concept Study on Cancer Detectability2025
  4. 4Conspicuity and characterization of pre-selected hypodense hepatic lesions in pancreatic cancer patients: limited clinical value of dual-energy portal phase CT2026
  5. 5Optimizing Arterial Vessel Contrast in Portal Venous Phase with Virtual Monoenergetic Images from Photon-Counting Detector CT Scans of the Abdomen—First Clinical Experiences2024 · 8 citations