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March 31, 2026International Journal of Molecular SciencesOpen Access

Correction: Vyas et al. Efficacy of Adeno-Associated Virus Serotype 9-Mediated Gene Therapy for AB-Variant GM2 Gangliosidosis. Int. J. Mol. Sci. 2023, 24, 14611

Meera Vyas Natalie M. Deschenes Karlaina J.L. Osmon Zhilin Chen Imtiaz Ahmad Shalini Kot Patrick Thompson Chris Richmond Steven J. Gray Jagdeep S. Walia

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Key Points

To assess the efficacy of adeno-associated virus serotype 9 (AAV9) gene therapy in treating AB-variant GM2 gangliosidosis.
Utilization of AAV9 vector for gene delivery
Evaluation of neurological function in affected models
Analysis of biochemical markers post-treatment
Significant improvements in neurological function observed
Reduction in GM2 ganglioside levels indicates successful gene therapy
Potential for improved quality of life after treatment

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Implication

Correction reports enhanced efficacy of gene therapy for GM2 gangliosidosis, indicating improved treatment strategies.

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Cite This Study

Vyas et al. (2026) studied this question.

synapsesocial.com/papers/69cd7b065652765b073a8a4b https://doi.org/10.3390/ijms27073166

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