Case report demonstrates successful tumor removal and functional recovery in an elderly patient with distal femoral GCT, suggesting effective treatment approaches.
Giant cell tumors (GCT) of the bone are mostly benign yet locally malignant neoplasms that afflict young adults. Although their incidence in older adults is limited, age-related factors and specific manifestations may cause diagnostic and therapeutic challenges. We described a rare case of distal femoral GCTs in a 68-year-old patient with increased knee soreness and decreasing mobility. Radiographic and pathological examinations confirmed a diagnosis involving Campanacci grade III GCT of the distal femur. Given the severity of bone degradation and the patient’s age, a limb-salvage procedure was performed utilizing a hinge knee megaprosthesis. The surgical procedure resulted in successful tumor removal with negative margins and stable prosthetic repair. At the 1-year follow-up, the patient healed functionally with no local recurrence or prosthetic issues. Although infrequent, GCTs in elderly people should be examined when identifying lytic bone lesions. Endo-prosthetic repair using a hinge knee mega prosthesis is a reliable limb-salvage option in appropriate conditions, offering pain relief, joint stability, and an improved quality of life.
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Sambare et al. (2026) studied this question.
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