Key result
Never receiving medication side effect information is linked to ~114% higher odds of low adherence post-PCI.
Why the study?
Effective patient education is fundamental to promoting post-PCI medication adherence, but educational gaps in Middle Eastern cardiac care settings remain inadequately explored.
Does poor medication-related communication quality reduce antiplatelet adherence in post-PCI patients?
Does poor medication-related communication quality reduce antiplatelet adherence in post-PCI patients?
Significant deficits in patient education regarding medication side effects and purpose are strongly associated with low antiplatelet adherence in post-PCI patients.
Background: Effective patient education is fundamental to promoting medication adherence following percutaneous coronary intervention (PCI). However, the extent and nature of educational gaps in Middle Eastern cardiac care settings remain inadequately explored. This study examined medication-related communication quality, patient knowledge gaps, and their associations with antiplatelet adherence among Saudi adults post-PCI. Methods: A cross-sectional survey was conducted among 236 Saudi adults who had undergone PCI within the preceding 12 months at two tertiary cardiac centres in Riyadh, Saudi Arabia. Data were collected using a structured questionnaire assessing clarity of medication information (side effects, dosing, purpose), medication knowledge, and adherence measured via the Arabic Morisky Medication Adherence Scale-8 (MMAS-8). Descriptive statistics, bivariate analyses, and multivariable logistic regression examined associations between communication quality indicators, sociodemographic factors, and adherence outcomes. Results: Substantial educational deficits emerged: (1) 26.3% never received side-effect information, (2) 11.0% never learned medication purpose, and (3) 6.8% did not identify their antiplatelet medication type. Only 40.5% consistently received clear medication explanations during hospitalization. Understanding of medication instructions was inadequate, with 14.0% reporting that they never understood their instructions. Adherence was suboptimal, with 54.9% demonstrating low adherence (MMAS-8 score < 6). In adjusted logistic regression, never receiving side-effect information was associated with higher odds of low adherence (adjusted OR 2.14, 95% CI 1.18–3.89) after controlling for age, sex, education, time since PCI, diabetes, and home support. Conclusions: Significant gaps in medication education and patient–provider communication exist within Saudi cardiac care settings. These deficits represent potentially modifiable targets for nursing intervention. Structured, nurse-led educational protocols addressing medication purpose, side effects, and administration could be evaluated as strategies to enhance patient understanding and support antiplatelet adherence.
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Aljuhani et al. (2026) studied this question. Never receiving medication side-effect information was associated with higher odds of low adherence (adjusted OR 2.14, 95% CI 1.18–3.89) among post-PCI patients.
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