November 1, 2015EuroIntervention
Association of spontaneous and procedure-related bleeds with short- and long-term mortality after acute coronary syndromes: an analysis from the PLATO trial
Why the study?
Does spontaneous bleeding compared to procedure-related bleeding increase short- and long-term mortality in patients with acute coronary syndromes?
Structured PICO
Does spontaneous bleeding compared to procedure-related bleeding increase short- and long-term mortality in patients with acute coronary syndromes?
P
Population
Patients with acute coronary syndromes (ACS) from the PLATO trial
I
Intervention
Spontaneous bleeding (as an exposure)
C
Comparator
Procedure-related bleeding
O
Outcome
Short- and long-term mortalityhard clinical
In patients with acute coronary syndromes, spontaneous bleeding carries a significantly stronger association with early mortality than procedure-related bleeding.
Authors
Discussion
No takes yet. Share an insight, caveat, or question.
Implication
May warrant intensified early surveillance for spontaneous bleeding in ACS; hypothesis-generating for etiology-specific prevention trials.
Cite This Study
Ducrocq et al. (2015) studied this question.