PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
April 20, 2015European Heart Journal366 citationsOpen Access

Bleeding and stent thrombosis on P2Y12-inhibitors: collaborative analysis on the role of platelet reactivity for risk stratification after percutaneous coronary intervention

View Full Paper
DADániel AradiAKAjay J. KirtaneLBLaurent Bonello

Key Points

  • To evaluate the role of platelet reactivity assessment in identifying patients at risk for mortality and stent thrombosis following percutaneous coronary intervention.
  • Conducted a collaborative analysis on patients treated with P2Y12-inhibitors after PCI.

Structured PICO

Does platelet reactivity assessment identify risk for mortality, stent thrombosis, and bleeding in PCI-treated patients on thienopyridine-type P2Y12-inhibitors?

P
Population
PCI-treated patients receiving thienopyridine-type P2Y12-inhibitors
I
Intervention
Platelet reactivity assessment
O
Outcome
Mortality, stent thrombosis (ST), and bleedinghard clinical

Platelet reactivity assessment can effectively stratify PCI patients on thienopyridines into high ischemic risk (HPR) or high bleeding risk (LPR) categories.

Abstract

Platelet reactivity assessment during thienopyridine-type P2Y12-inhibitors identifies PCI-treated patients at higher risk for mortality and ST (HPR) or at an elevated risk for bleeding (LPR).

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Aradi et al. (2015) studied this question.

synapsesocial.com/papers/69cea11e5ff5f19319758b59https://doi.org/10.1093/eurheartj/ehv104
Ask AI
Helpful
Bookmark
Share
View Full Paper

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prasugrel versus Clopidogrel in Patients with Acute Coronary Syndromes2007 · 6,811 citations
  2. 2Consensus and Update on the Definition of On-Treatment Platelet Reactivity to Adenosine Diphosphate Associated With Ischemia and Bleeding2013 · 907 citations
  3. 3Bedside Monitoring to Adjust Antiplatelet Therapy for Coronary Stenting2012 · 882 citations
  4. 4Standard- vs High-Dose Clopidogrel Based on Platelet Function Testing After Percutaneous Coronary Intervention2011 · 1,306 citations
  5. 5Point-of-Care Measurement of Clopidogrel Responsiveness Predicts Clinical Outcome in Patients Undergoing Percutaneous Coronary Intervention2008 · 353 citations