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Findings reveal the importance of TP53 mutations in predicting outcomes in metastatic colorectal cancer, suggesting therapeutic strategies.
TP53 mutations appear to be an independent prognostic marker for prolonged progression-free survival in patients with metastatic colorectal cancer. Although the difference in overall survival was not statistically significant, these findings warrant further validation in prospective studies to confirm the prognostic utility of TP53 in therapeutic stratification.
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Yıldız et al. (2026) studied this question.
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