Demonstrates enhanced immune activation in HPV-associated oropharyngeal squamous cell carcinoma, suggesting implications for treatment strategies.
Our findings highlight the role of FBLN1+ FRCs in fostering immune activation within the TME of HPV-associated OPSCC. Enhanced antigen presentation and epithelial proliferation likely facilitate tumor-immune interactions, contributing to better clinical outcomes. This study advances the understanding of TME dynamics in OPSCC and may inform future therapeutic strategies.
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Gu et al. (2026) studied this question.
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