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March 31, 2026Journal of Clinical Research in Pediatric EndocrinologyOpen Access

Subclinical Hypothyroidism in Children: Natural History, Risk Factors, and Outcomes

Nur Şeyma Zengin Elif Sağsak Seda Geylanı Güleç

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Key Points

To explore the natural history, risk factors, and outcomes of subclinical hypothyroidism in children.
Analyzed the progression of subclinical hypothyroidism in pediatric patients
Evaluated risk factors such as hashimoto's thyroiditis and baseline TSH levels
Assessed growth stability in children diagnosed with mild SH
Identified that pediatric subclinical hypothyroidism is usually benign and self-limited
Found that Hashimoto's thyroiditis and higher TSH levels predict progression
Confirmed that growth remains stable in idiopathic cases

Implication

Examines outcomes of subclinical hypothyroidism in children, indicating the importance of individualized management.

Discussion

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Cite This Study

Zengin et al. (2026) studied this question.

synapsesocial.com/papers/69cf5c925a333a821460a19d https://doi.org/10.4274/jcrpe.galenos.2026.2025-9-27

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Evaluation of the etiology of subclinical hypothyroidism in children2024
2Heterozygous TSHR Variants in Pediatric Idiopathic Subclinical Hypothyroidism: Association with a Variable and Compensated Thyroid PhenotypeOriginal Research · 2026
3Pattern and Predictors of Thyroid Dysfunction among Pediatric Endocrine Referrals at the Tertiary Care Center of Northern India: A Longitudinal Study2024
4Hashimoto’s thyroiditis in children and adolescents: analysis of long-term course2025
5Diagnosis of Thyroid Nodules in Children and Adolescents with Subclinical Hypothyroidism and Their Outcomes after Early Thyroxine Treatment—A Longitudinal Study2024 · 2 citations