Case-control study shows links between prescribed medications and Clostridioides difficile infections, suggesting careful prescribing practices.
We found varying effects of antibiotics on CDI, providing evidence for ongoing efforts in prudent prescribing decisions and antimicrobial stewardship. We confirmed PPI as a main risk factor for CDI and provided new evidence for other non-antibiotic drugs as potentially important risk factors considering their high prescription prevalence.
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Boven et al. (2026) studied this question.
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