Exploratory study finds antibacterial effects of natural extracts in foodborne pathogens, suggesting new treatments.
BACKGROUND: Antimicrobial resistance among foodborne pathogens poses a growing public health challenge, particularly in low-resource settings, necessitating exploration of plant-derived antibacterial agents. MATERIALS AND METHODS: This retrospective exploratory laboratory-based study was conducted at Stamford University, Bangladesh, Dhaka. Ethanol and methanol extracts of Terminalia chebula, Capsicum annuum, Cuminum cyminum , and Coriandrum sativum were evaluated against nine Salmonella spp. and five Escherichia coli clinical isolates using the agar well diffusion method. Statistical analysis was performed using GraphPad Prism, with significance set at P < 0.05. RESULTS: Ethanolic extracts, particularly of T. chebula, C. annuum , demonstrated significantly higher antibacterial activity against Salmonella spp. compared with methanolic extracts ( P < 0.05). Limited and strain-dependent activity was observed against E. coli . CONCLUSION: Selected extracts exhibit moderate antibacterial activity against multidrug-resistant Salmonella spp., supporting their potential role as supplementary antimicrobial agents.
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Islam et al. (2026) studied this question.
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