Bushen Huoxue Formula Enema Improves Embryo Implantation: Promoting Epithelial–Mesenchymal Transition via the LXA4R/NF‐κB Pathway

Can Zhu; Wanting Xia; Hang Zhou; Xuan Zhang; Yi Wang; Jinzhu Huang; Qian Zeng

doi:10.1111/aji.70231

April 1, 2026American Journal of Reproductive Immunology

Bushen Huoxue Formula Enema Improves Embryo Implantation: Promoting Epithelial–Mesenchymal Transition via the LXA4R/NF‐κB Pathway

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Key Points

The study aims to evaluate the effects of Bushen Huoxue Formula enema on embryo implantation and the underlying molecular mechanisms.
Applied Bushen Huoxue Formula enema in experimental models.
Monitored changes in the LXA4R/NF-κB pathway related to embryo implantation.
Assessed the promotion of epithelial-mesenchymal transition in target tissues.
BHF enema significantly improved embryo implantation rates.
Activation of the LXA4R/NF-κB pathway was observed post-treatment.
Epithelial-mesenchymal transition was enhanced, supporting implantation success.

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Implication

BHF enema improves embryo implantation in disorders, indicating its therapeutic potential for reproductive health.

Abstract

BHF enema improves embryo implantation by modulating the LXA4R/NF-κB pathway to promote EMT, highlighting its potential as a treatment for embryo implantation disorders.

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Cite This Study

Zhu et al. (2026) studied this question.

synapsesocial.com/papers/69cf5d605a333a821460b137 https://doi.org/10.1111/aji.70231

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Bushen Huoxue Formula Enema Improves Embryo Implantation: Promoting Epithelial–Mesenchymal Transition via the LXA4R/NF‐κB Pathway

Key Points

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Implication

Abstract

Discussion

Cite This Study

Bushen Huoxue Formula Enema Improves Embryo Implantation: Promoting Epithelial–Mesenchymal Transition via the LXA4R/NF‐κB Pathway

Key Points

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Implication

Abstract

Discussion

Cite This Study

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