Multiethnic Cohort Study reveals shared and distinct risk factors for ductal carcinoma in situ and invasive breast cancer in diverse women.
Key Points
This research investigates the risk factors for ductal carcinoma in situ (DCIS) and compares them with those for invasive breast cancer.
Utilized data from the Multiethnic Cohort Study
Examined associations of known breast cancer risk factors with DCIS in a diverse population
Analyzed risk across different racial and ethnic groups
African American, Native Hawaiian, and Japanese American women exhibited significantly higher risk of DCIS compared to White women
Increased risk associated with family history of breast cancer, type 2 diabetes, nulliparity, older age at first live birth, and current estrogen hormone therapy
Parity and non-U.S. birthplace were associated with decreased DCIS risk
Smoking status showed increased risk only among Native Hawaiians