Case report identifies diffuse organ infiltration and uptake in a patient with multiple myeloma, suggesting rare presentation.
Patients with multiple myeloma (MM) presenting diffuse extramedullary infiltration of the liver and spleen are extremely rare. Here we present the 18F-FDG PET/CT findings of a 53-year-old man who complained of eyelids swelling for more than 4 months. The 18F-FDG PET/CT demonstrated diffuse intense uptake in the bone, liver, and spleen. Finally, the diagnosis of MM with hepatic and splenic involvement was confirmed.
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Zhao et al. (2026) studied this question.
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