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Evaluate the risk of hypertensive complications in oocyte donation pregnancies compared to autologous pregnancies.

The risk for the development of hypertensive complications in oocyte donation pregnancy: a systematic review and individual participant data meta-analysis (DONOR IPD)

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Evaluate the risk of hypertensive complications in oocyte donation pregnancies compared to autologous pregnancies.
Conducted a systematic literature search across multiple databases.
Included observational studies comparing oocyte donation pregnancies to autologous pregnancies post 20 weeks gestation.
Performed a one- and two-stage meta-analysis adjusting for potential confounders.
Conducted sensitivity, meta-regression, and subgroup analyses.
OD pregnancies show a two-fold higher risk for hypertensive complications compared to autologous pregnancies.
Adjusted ORs reveal increased risks for pregnancy-induced hypertension and preeclampsia.
Subgroup analyses indicate these risks persist across various maternal characteristics and contexts.

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A systematic review reveals increased hypertensive risks in oocyte donation pregnancies, suggesting need for awareness among healthcare providers.

Bentem et al. (2026) studied this question.

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A systematic review reveals increased hypertensive risks in oocyte donation pregnancies, suggesting need for awareness among healthcare providers.