Findings demonstrate that PIM1 regulates DDX41-STING signaling to alleviate keratitis caused by Aspergillus fumigatus, suggesting a new treatment approach.
Our findings reveal a novel mechanism by which PIM1 aggravates A. fumigatus keratitis through activation of the DDX41-STING signaling axis, highlighting PIM1 as a promising therapeutic target for FK.
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Han et al. (2026) studied this question.
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