Prospective trial reveals neurocognition disruption in pediatric patients after proton beam radiotherapy, indicating need for mitigation strategies.
Compared with HCs, pediatric patients after PBRT displayed significant disruption in several RSNs, notably between SN and DMN critical in neurocognitive control. Dose-dependent neurocognition and QoL impairment warrant further investigation for mitigation.
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Tringale et al. (2026) studied this question.
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