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April 3, 2026Transplant Infectious Disease2 citations

Outcomes of Short Antibiotic Courses for Gram‐Negative Bloodstream Infections in Solid Organ Transplant Recipients—A Systematic Review and Meta‐Analysis

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MAMuath A. M. AlotaibiAAAbdulellah AlmohayaRBRoni Bitterman

Key Points

  • To evaluate the effectiveness of short versus long antibiotic courses for gram-negative bloodstream infections in solid organ transplant recipients.
  • Conducted a systematic review of existing trials
  • Analyzed treatment durations
  • Compared outcomes of short and long antibiotic therapies
  • No statistically significant differences in outcomes between treatment durations were found
  • Limited sample size hampers firm conclusions
  • A need for larger, high-quality studies was identified

Abstract

Our review underscores the importance of including SOT recipients in trials comparing short versus long antibiotic therapy for GN-BSIs. Although no statistically significant differences were observed between treatment durations, the limited sample size precludes definitive conclusions and highlights the need for larger, high-quality studies.

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Cite This Study

Alotaibi et al. (2026) studied this question.

synapsesocial.com/papers/69cf5e3d5a333a821460c6d5https://doi.org/10.1111/tid.70209
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