Quantitative analysis identifies microvascular changes in non-arteritic anterior ischemic optic neuropathy, suggesting bilateral risk.
Chronic non-arteritic anterior ischaemic optic neuropathy is associated with persistent neuroaxonal thinning and microvascular reduction. Fellow eyes exhibit a disc-at-risk configuration and subtle peripapillary perfusion changes, suggesting bilateral anatomical susceptibility. Optical coherence tomography and optical coherence tomography angiography may help identify subclinical vulnerability and support longitudinal monitoring.
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Özdemir et al. (2026) studied this question.
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