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This research examines how UV photofunctionalization influences cellular behavior and implant stability.

April 3, 2026OdontologyOpen Access

Evaluation of the effects of ultraviolet photofunctionalization on titanium surfaces: in vitro and in vivo study

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In vitro and clinical trials evaluate UV effects on titanium implants, indicating improved stability.

This research examines how UV photofunctionalization influences cellular behavior and implant stability.
Conducted in vitro tests on smooth and sandblasted acid-etched titanium disks.
Assessed wettability, roughness, cytotoxicity, cell proliferation, adhesion, and type I collagen production.
Performed a clinical trial on ten patients with UV-irradiated and non-irradiated implants.
Measured implant stability using the Osstell device over 14 weeks.
UV irradiation significantly improved wettability and surface roughness (p < 0.05).
Cell proliferation increased in the UV-irradiated group at 48 hours (p < 0.05).
UV-irradiated implants showed greater stability during certain measurement intervals (p < 0.05).
No significant differences in cytotoxicity or type I collagen levels among groups.

Pavei et al. (2026) studied this question.

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