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The aim was to evaluate the effectiveness and tolerability of ADHD treatments through a systematic review of meta-analyses.

New Tool Summarizes the Evidence for ADHD Treatment Options

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The aim was to evaluate the effectiveness and tolerability of ADHD treatments through a systematic review of meta-analyses.
Conducted a systematic review of 115 meta-analyses on ADHD interventions.
Extracted data on effectiveness, tolerability, and acceptability for specific treatments.
Rated certainty of evidence and analyzed outcomes based on different rating groups.
Found moderate to high certainty that methylphenidate and amphetamines improved ADHD symptoms in children and adolescents in the short term.
Cognitive behavioral therapy exhibited large effect sizes but with low certainty.
In adults, both methylphenidate and atomoxetine showed short-term effectiveness with high certainty.

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An umbrella review shows short-term efficacy of ADHD interventions in various age groups, indicating diverse treatment choices.

A 2026 study studied this question.

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