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April 3, 2026Langenbeck s Archives of SurgeryOpen Access

Development of novel criteria for drain removal after pancreaticogastrostomy in pancreaticoduodenectomy: a retrospective analysis and validation study at a single institution

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Authors

HMHisashi MurakamiToranomon HospitalSOSatoshi OkuboToranomon HospitalTOTakuma OkadaIzumi City General Hospital

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Implication

Retrospective analysis develops drain removal criteria in pancreaticoduodenectomy, suggesting safer management.

Key Points

  • This research aims to create and validate new criteria for the safe removal of drains after pancreaticogastrostomy following pancreaticoduodenectomy.
  • Conducted a retrospective analysis of 195 pancreaticoduodenectomy cases.
  • Identified independent risk factors via multivariate analysis.
  • Developed new criteria for drain removal based on identified risk factors.
  • Validated criteria in a prospective cohort of 70 soft pancreas cases.
  • Assessed patient outcomes post-drain removal.
  • Identified risk factors included WBC > 8200/µL and DFA > 160 U/L on postoperative day 5.
  • Defined criteria for safe drain removal as WBC ≤ 8200/µL, DFA ≤ 160 U/L, and NG tube removal by POD 5.
  • In validation cohort, 42 out of 70 patients met criteria with no grade IIIa or higher complications.
  • Reduced incidence of delayed gastric emptying in the post-validation cohort compared to pre-validation cohort (p < 0.01).

Cite This Study

Murakami et al. (2026) studied this question.

synapsesocial.com/papers/69cf5f505a333a821460e709https://doi.org/10.1007/s00423-026-04040-3
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