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April 3, 2026Bioengineering2 citationsOpen Access

Ultrasound-Guided Targeted Injection to the Anterior Labral–Ligamentous Complex of the Shoulder: A Cadaveric Feasibility Study for Regenerative Therapy

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SKSang-Hyun KimULU.-Young LeeYYYonghyun Yoon

Key Points

  • This study aims to assess the feasibility and accuracy of ultrasound-guided injections to the anterior labral-ligamentous complex in cadaveric shoulders.
  • Conducted ultrasound scanning to localize the ALLC in a fresh-frozen cadaver specimen.
  • Injected 1-2 mL of red filler using a 23-gauge needle into the ALLC.
  • Performed layer-by-layer dissection post-injection to evaluate the distribution of injectate.
  • Red filler was successfully confined within the ALLC in both shoulders without any leakage.
  • No evidence of intra-articular pooling or neurovascular staining was observed.
  • Findings confirm the anatomical feasibility of ultrasound-guided injection targeting the ALLC.

Abstract

The anterior labral–ligamentous complex (ALLC), formed by the integration of the anterior inferior glenohumeral ligament and anterior glenoid labrum, plays a critical role in shoulder stability and represents a potential target for regenerative injection therapy. However, precise ultrasound-guided targeting of this capsular–labral interface has not been anatomically validated. This feasibility cadaveric study evaluated the accuracy of ultrasound-guided in-plane injection directed at the ALLC at its glenoid attachment. A fresh-frozen human cadaver specimen was examined in the supine position with the shoulder in external rotation. Stepwise lateral-to-medial and cranial-to-caudal ultrasound scanning was performed to localize the ALLC. A 23-gauge needle was advanced in a cranial-to-caudal in-plane trajectory, and 1–2 mL of red filler was injected into the capsular–labral interface. Subsequent layer-by-layer dissection was conducted to assess injectate localization. In both shoulders (2/2), red filler was confined within the ALLC without extra-capsular leakage, diffuse intra-articular pooling, or neurovascular staining. These findings demonstrate the anatomical feasibility of ultrasound-guided targeted delivery to the anterior capsular–labral complex. This proof-of-concept study provides foundational anatomical validation for the development of regenerative injection protocols directed at the shoulder capsular–labral enthesis.

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Cite This Study

Kim et al. (2026) studied this question.

synapsesocial.com/papers/69cf5f645a333a821460e901https://doi.org/10.3390/bioengineering13040418
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