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This study investigates how women at elevated risk of ovarian cancer prioritize treatment options based on their preferences and health attributes.

April 3, 2026JAMA Network OpenOpen Access

Patient Preferences for Ovarian Cancer Risk–Reducing Treatments Revealed Through Choice Experiments

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This study investigates how women at elevated risk of ovarian cancer prioritize treatment options based on their preferences and health attributes.
Participants completed a demographic survey and treatment education.
A conjoint analysis evaluated preferences using hypothetical treatment scenarios.
355 women were surveyed before and after genetic testing disclosure.
Interactions among demographics and cancer history were analyzed.
Women preferred salpingo-oophorectomy over salpingectomy (odds ratio 1.24).
Preferences were less influenced by the timing of genetic test disclosures.
Menopausal risks diminished preferences for surgery, yet optimal risk reduction remained the priority.

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Daly et al. explore decision-making in ovarian cancer risk reduction among women with familial histories, indicating implications for counseling.

Ilana Cass (2026) studied this question.

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Daly et al. explore decision-making in ovarian cancer risk reduction among women with familial histories, indicating implications for counseling.