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April 4, 2026Journal of PACSOpen Access

Diffuse Large B-Cell Lymphoma of the Thyroid Presenting with Biphasic Stridor and Respiratory Failure: Case Report

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Authors

MCMahendran CSDPDeepak PrajapatPoornima UniversityKSKshitiz SinghUniversity of Kentucky

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Implication

Case report reveals life-threatening airway obstruction from thyroid lymphoma, indicating need for prompt diagnosis and intervention.

Key Points

  • This report aims to examine an unusual presentation of diffuse large B-cell lymphoma in the thyroid leading to respiratory complications.
  • Detailed imaging studies including CECT neck and HRCT chest were performed.
  • USG-guided biopsy was conducted to diagnose thyroid mass.
  • Patient received micafungin, IV antibiotics, serial bronchoscopy, and supportive therapy.
  • The diagnosis of diffuse large B-cell lymphoma was confirmed via biopsy.
  • Patient exhibited rapidly worsening respiratory failure requiring intubation.
  • Successful stabilization followed initiation of a nonsurgical rituximab-based therapy.

Cite This Study

CS et al. (2026) studied this question.

synapsesocial.com/papers/69d0adc2659487ece0fa44b5https://doi.org/10.5005/jpacs-11047-0023
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1CHOP Chemotherapy plus Rituximab Compared with CHOP Alone in Elderly Patients with Diffuse Large-B-Cell Lymphoma2002 · 5,634 citations
  2. 2Malignant Lymphoma of the Thyroid Gland2000 · 418 citations
  3. 3Rituximab-Including Combined Modality Treatment for Primary Thyroid Lymphoma: An Effective Regimen for Elderly Patients2014 · 26 citations
  4. 4Usefulness of Ultrasonography for Diagnosis of Malignant Lymphoma of the Thyroid2006 · 116 citations