diagnosis of pleural effusion.Recognizing this gap, the present study aimed to assess the effectiveness of the dipstick method in diagnosing pleural effusion by comparing its results with well-established diagnostic standards, such as Light's criteria, microbiological findings, and cytological analysis.The objective was to determine how closely the results obtained from the dipstick test align with these conventional methods, particularly in differentiating transudative from exudative effusions, and identifying infective vs noninfective causes.By doing so, the study seeks to evaluate whether dipstick testing can serve as a rapid, cost-effective, and reliable point-of-care tool for initial pleural effusion assessment, potentially improving diagnostic efficiency in clinical practice. IntroductIonPleural effusion is characterized by the collection of surplus fluid in the pleural space, which is a common clinical finding associated with a broad spectrum of pulmonary and extrapulmonary conditions. 122]3 Pleural effusions are generally classified into 2 primary types based on their underlying pathophysiology: transudative effusions, arising from imbalances in hydrostatic or oncotic pressures, and exudative effusions, resulting from inflammation, infection, or malignancy, which increase capillary permeability. 4Exudative effusion is further differentiated into infectious or noninfectious. 5These distinctions are critical for selecting the proper treatment, such as drainage of an infectious exudative effusion, therapy for heart failure, microbiological documentation, and suitable antibiotics for empyema. 677]8 Dipstick testing for leukocyte esterase activity has been used to quickly diagnose infection in a variety of bodily fluids, including pleural fluid, cerebrospinal fluid, and urine.It has also been verified to measure the pH of pleural effusions. 7,9100]1112 Several recent studies have demonstrated the effectiveness of dipsticks in diagnosing spontaneous bacterial peritonitis. 13144]15 However, there are very few studies in which reagent strips were tested for their ability to accurately assess the leukocyte esterase in pleural fluid and quantities of protein, which are the 2 most essential criteria in distinguishing transudate from exudates. 1617]18 Currently, there are no published studies in South Indian literature that evaluate the role of dipstick testing in the 1-
KS et al. (Tue,) studied this question.