What question did this study set out to answer?

This trial aims to compare the effectiveness and safety of mixed reality versus computed tomography-guided localization for pulmonary nodules in video-assisted thoracoscopic surgery.

April 4, 2026Scientific ReportsOpen Access

Comparison of mixed reality and computed tomography-guided preoperative hook-wire localization for pulmonary nodules in video-assisted thoracoscopic surgery: a noninferiority randomized clinical trial

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Authors

WQWenzhe QiCivil Aviation University of China JZJuan Zhou117th Hospital of People's Liberation Army NXNing XinSecond Hospital of Shandong University

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Implication

Noninferiority randomized trial compares mixed reality and CT-guided preoperative localization for pulmonary nodules, suggesting improved efficiency and safety.

Key Points

This trial aims to compare the effectiveness and safety of mixed reality versus computed tomography-guided localization for pulmonary nodules in video-assisted thoracoscopic surgery.
Conducted a noninferiority randomized clinical trial at a single center
Enrolled 90 patients with small pulmonary nodules
Patients were randomized into mixed reality or CT-guided localization groups
Measured accuracy, procedural duration, radiation exposure, and complications
MR-guided localization achieved higher accuracy with smaller deviations (5.50 mm vs. 6.84 mm, p = 0.04)
Significantly reduced procedural duration in MR-guided group (3.98 min vs. 10.73 min, p < 0.001)
Fewer insertion attempts in MR-guided group (1.05 vs. 2.28, p < 0.001)
Lower radiation exposure in MR group (p < 0.001)
Surgical outcomes were comparable between both groups.

Cite This Study

Qi et al. (2026) studied this question.

synapsesocial.com/papers/69d0aeb9659487ece0fa4a87 https://doi.org/10.1038/s41598-026-47315-x

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Implication

Noninferiority randomized trial compares mixed reality and CT-guided preoperative localization for pulmonary nodules, suggesting improved efficiency and safety.

Comparison of mixed reality and computed tomography-guided preoperative hook-wire localization for pulmonary nodules in video-assisted thoracoscopic surgery: a noninferiority randomized clinical trial

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Implication

Key Points

Cite This Study

Comparison of mixed reality and computed tomography-guided preoperative hook-wire localization for pulmonary nodules in video-assisted thoracoscopic surgery: a noninferiority randomized clinical trial

Discussion

Member takes

Implication

Key Points

Cite This Study

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