What question did this study set out to answer?

This research aims to understand how antimicrobial pressures affect the evolution of Vibrio species over time.

April 4, 2026Open Access

A decade of antimicrobial resistance in Vibrio spp.: genomic and functional insights

APAgila Kumari PragasamTranslational Health Science and Technology Institute CBChandana BasakTranslational Health Science and Technology Institute MRMansi RajwanshiTranslational Health Science and Technology Institute

Key Points

This research aims to understand how antimicrobial pressures affect the evolution of Vibrio species over time.
Analyzed clinical isolates from a cholera-endemic region over 16 years
Examined both known and novel resistance mechanisms
Evaluated virulence factors in emerging Vibrio paracholerae cases
Documented increase in multidrug resistance among Vibrio species
Identified new genomic resistance mechanisms and virulence factors
Emphasized need for ongoing genomic surveillance to manage cholera effectively

Abstract

This study highlights how long-term environmental and antimicrobial pressures shape the evolution of Vibrio species, leading to multidrug resistance and genomic diversification. By analyzing 16 years of clinical isolates from a major cholera-endemic region in India, including emerging Vibrio paracholerae cases, we reveal both known and novel resistance mechanisms and virulence factors. These findings emphasize the need for sustained genomic surveillance to track evolving resistance trajectories and support effective control strategies for cholera and related enteric infections in endemic regions.

KI fragen

Bookmark

View Full Paper