A case report demonstrates challenges in diagnosing IgA vasculitis in travelers, suggesting awareness is vital.
IgA vasculitis, formerly known as Henoch-Schönlein purpura, is an immune complex-mediated small-vessel vasculitis that primarily affects children but may occur in adults, where it carries a higher risk of systemic complications, particularly renal involvement. Adult-onset disease is frequently underrecognized and may lack classic features, instead mimicking infectious, autoimmune, or drug-related conditions, thereby delaying diagnosis. In patients with persistent purpura and an unrevealing initial workup, vasculitis should remain in the differential diagnosis. We present the case of a patient diagnosed with IgA vasculitis following recent international travel, highlighting the diagnostic challenges and clinical reasoning that ultimately led to the diagnosis.
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AKULA et al. (2026) studied this question.
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