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April 4, 2026Open Access

Occurrence of Chronic Pulmonary Aspergillosis in Pulmonary Tuberculosis: A Hospital-Based Cross-Sectional Study

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Authors

SPShivangi PriyadarshaniSCSatyadeo ChoubeyAEArshad Ejazi

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Implication

Cross-sectional analysis finds high chronic pulmonary aspergillosis occurrence in pulmonary tuberculosis patients, suggesting need for better diagnostics.

Key Points

  • Examine the occurrence of chronic pulmonary aspergillosis in patients with pulmonary tuberculosis and its associations.
  • Enrolled 143 adults from outpatient and inpatient departments
  • Included newly and previously diagnosed pulmonary tuberculosis patients
  • Diagnosis of CPA based on symptoms, radiological findings, and microbiological/immunological evidence
  • Utilized STATA 14.0 for data analysis with descriptive and comparative statistics
  • 34.3% of pulmonary tuberculosis patients diagnosed with chronic pulmonary aspergillosis
  • Male predominance in CPA patients with a male-to-female ratio of 4:1
  • Associations found with diabetes mellitus (70.8%, p=0.038) and post-tuberculosis lung disease (61.4%, p=0.040)
  • Radiological features like cavitation (47.4%, p=0.009) and aspergilloma (55.9%, p=0.009) more frequent in CPA patients
  • 69.4% of CPA patients positive for Aspergillus-specific IgG (p<0.001)

Cite This Study

Priyadarshani et al. (2025) studied this question.

synapsesocial.com/papers/69d0af83659487ece0fa572bhttps://doi.org/10.71480/nmj.v66i6.1154
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Chronic pulmonary aspergillosis incidence in newly detected pulmonary tuberculosis cases during follow-up2024 · 1 citations
  2. 2Chronic pulmonary aspergillosis incidence in newly detected pulmonary tuberculosis cases during follow‐up2024 · 11 citations
  3. 3Incidence and prevalence of chronic pulmonary aspergillosis in patients with post‐tuberculosis lung abnormality: Results from a community survey in North India2024 · 8 citations
  4. 4Prevalence of Chronic Pulmonary Aspergillosis in Two (2) Tuberculosis Treatment Clinics in Lagos, Nigeria: A Prospective Longitudinal Study2024 · 13 citations
  5. 5ASPERGILLOSIS AND POST-TUBERCULOSIS LUNG DISEASE: A RELEVANT AND NEGLECTED ASSOCIATION2026