Histological and epigenetic alterations in vaginal relaxation syndrome: evidence from m6A-Seq, RNA-Seq, and animal models

Key Points

• The research aims to explore the molecular and histological changes associated with vaginal relaxation syndrome (VRS).
• Utilized m6A-seq and RNA-seq for epigenetic and transcriptomic analysis
• Employed animal models to study VRS
• Analyzed histological changes in vaginal tissues
• Identified significant epigenetic alterations in VRS samples
• Observed distinct histological remodeling linked to disease pathology
• Suggested potential biomarkers and therapeutic targets related to epigenetic regulation