Patients with chronic heart failure exhibit potentiated ventilatory and sympathetic responses to hypercapnia-induced central chemoreceptor activation.
Hypothesis-generating for chemoreflex modulation in HF; prospective trials needed before clinical consideration.
Chronic heart failure is characterized by a selective potentiation of ventilatory and sympathetic responses to central chemoreceptor activation by hypercapnia.
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Narkiewicz et al. (1999) studied this question.
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