What question did this study set out to answer?

This study aims to investigate the impact of in-hospital SARS-CoV-2 infection on clinical outcomes and costs for heart failure patients in Brazil.

April 5, 2026SHILAP Revista de lepidopterologíaOpen Access

Impact of in-hospital SARS-CoV-2 infection on mortality and outcomes in patients admitted for heart failure: a nationwide analysis in Brazil

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Authors

ABAdriana Aparecida BauUniversidade Estadual de Campinas (UNICAMP)CMCamila Nicolela Geraldo MartinsUniversidade Estadual de Campinas (UNICAMP)ACA. Coy-CanguçuUniversidade Estadual de Campinas (UNICAMP)

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Implication

This retrospective study analyzes the effects of COVID-19 on hospitalization outcomes in heart failure patients, highlighting increased mortality and healthcare costs.

Key Points

This study aims to investigate the impact of in-hospital SARS-CoV-2 infection on clinical outcomes and costs for heart failure patients in Brazil.
Conducted a retrospective analysis of 262,758 adults hospitalized for heart failure in Brazil
Compared outcomes between patients infected with COVID-19 and those who were uninfected
Analyzed demographics, comorbidities, clinical outcomes, and costs using Cox regression models
COVID-19 patients had longer hospital stays (median 7 days vs. 5 days; p < 0.001)
Higher renal replacement therapy needs in COVID-19 patients (6.5% vs. 2.6%; p < 0.001)
In-hospital mortality was greater in COVID-19 patients (26% vs. 13%; p < 0.001)
Hospitalization costs were significantly higher in the COVID-19 group (median BRL 1,373 vs. BRL 836; p < 0.001)
COVID-19 increased the risk of in-hospital death by 43% (HR 1.43; p = 0.001)

Cite This Study

Bau et al. (2026) studied this question.

synapsesocial.com/papers/69d1fb20a79560c99a0a183c https://doi.org/10.3389/fcvm.2026.1723680

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Implication

This retrospective study analyzes the effects of COVID-19 on hospitalization outcomes in heart failure patients, highlighting increased mortality and healthcare costs.

Impact of in-hospital SARS-CoV-2 infection on mortality and outcomes in patients admitted for heart failure: a nationwide analysis in Brazil

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Implication

Key Points

Cite This Study

Impact of in-hospital SARS-CoV-2 infection on mortality and outcomes in patients admitted for heart failure: a nationwide analysis in Brazil

Discussion

Member takes

Implication

Key Points

Cite This Study

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