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April 5, 2026SHILAP Revista de lepidopterologíaOpen Access

Deciphering the functions of NELL2 in tumorigenesis and beyond

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Authors

BLBing LiCFCong FuYRYuning Ren

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Overview

Research demonstrates NELL2's role in tumorigenesis across various contexts, suggesting new therapeutic avenues.

Key Points

  • This research aims to clarify the diverse roles of NELL2 in cancer and other physiological processes.
  • Consolidated existing research on NELL2
  • Analyzed structural features and regulatory networks
  • Delineated roles in neurodegeneration, immunity, reproduction, and cancer
  • NELL2 functions as both an oncogene and tumor suppressor in different contexts
  • Identified complexities in NELL2 signaling pathways
  • Highlighted potential applications for precision medicine targeting NELL2

Cite This Study

Li et al. (2026) studied this question.

synapsesocial.com/papers/69d1fb20a79560c99a0a183fhttps://doi.org/10.3389/fimmu.2026.1780909
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