Editorial: Innovative insights into pattern recognition and signaling in innate immunity

April 1, 2026Frontiers in ImmunologyOpen Access

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Key Points

This collection addresses how pattern recognition and signaling in innate immunity are interconnected, influencing immune responses.
Review of various studies on signaling pathways and pattern recognition in innate immunity
Analysis of functional roles of immune mediators and their connections to disease
Integration of findings across different disease contexts
Cytoplasmic ATM drives TBK1 activation and antiviral response, expanding its function beyond DNA repair.
C1q and surfactant protein D serve as multifunctional immune surveillance molecules.
Innate immune signaling pathways influence chronic inflammation and treatment responses across diseases.

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Editorial reveals new mechanisms of innate immunity signaling and pattern recognition, highlighting therapeutic potential.

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Granucci et al. (2026) studied this question.

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