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PDA treatment affects oxygen needs and lung function in ventilated preterm infants, suggesting careful monitoring is necessary.
PDA treatment in ventilated preterm infants was associated with an increase in the oxygen requirement during ventilation, a worsening of the ventilation to perfusion matching while it had a positive effect in reducing the level of the intrapulmonary right-to-left shunting.
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Marangoni et al. (2026) studied this question.
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