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April 5, 2026Frontiers in Molecular BiosciencesOpen Access

Breast milk miRNAs and their potential role in the development of atopy in infants

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Authors

APAdrianna PorebskaMedical University of WarsawMMMaciej MajMedical University of WarsawARAizhan RakhmetullinaInstitute of Biochemistry and Biophysics, Polish Academy of Sciences

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Implication

This review examines how maternal atopic status influences breast milk microRNA composition and atopy risk in infants, suggesting implications for early prevention.

Key Points

  • To explore the relationship between breast milk microRNA profiles and the development of atopy in infants, focusing on maternal atopic conditions.
  • Reviewed four relevant studies
  • Analyzed the impact of maternal atopic status on breast milk miRNA signatures
  • Investigated associations between specific miRNAs and infant atopy outcomes
  • Maternal atopy is linked to distinct breast milk miRNA profiles.
  • Elevated miR-375-3p levels correlate with a lower risk of infant atopic conditions.
  • Higher miR-1290 levels are found in atopic mothers, indicating its potential as a biomarker.

Cite This Study

Porebska et al. (2026) studied this question.

synapsesocial.com/papers/69d1fb20a79560c99a0a18d4https://doi.org/10.3389/fmolb.2026.1768239
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