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April 5, 2026Journal of the Faculty of Medicine BaghdadOpen Access

The Role of YKL-40 in the Diagnosis of Placenta Accreta Spectrum in a Group of Iraqi Patients

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Authors

NMNajmah M. MeranZMZina Mohammed

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Overview

Case-control study evaluates YKL-40 as a biomarker for placenta accreta spectrum severity in pregnant women, suggesting its diagnostic potential.

Key Points

  • To assess the relationship between maternal serum YKL-40 levels and the severity of placenta accreta spectrum.
  • Conducted a case-control study at Baghdad Teaching Hospital.
  • Included 97 pregnant women in their third trimester: 37 with placenta accreta spectrum and 60 controls with normal placenta.
  • Measured serum YKL-40 levels in both groups.
  • Higher mean YKL-40 levels found in patients with placenta accreta spectrum compared to controls.
  • YKL-40 cut-off point of 112.68 pg/ml associated with the diagnosis of placenta accreta spectrum.
  • Significant correlation between YKL-40 levels and depth of placental invasion.

Cite This Study

Meran et al. (2026) studied this question.

synapsesocial.com/papers/69d1fba0a79560c99a0a1b95https://doi.org/10.32007/jfacmedbaghdad3263
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