What question did this study set out to answer?

This study aims to analyze clinical characteristics of anti-amphiphysin-IgG-positive autoimmune syndrome and its association with related syndromes and tumors.

April 5, 2026SHILAP Revista de lepidopterologíaOpen Access

Anti-amphiphysin antibody positive autoimmune syndrome: case series and literature review

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Authors

LWLu WangWannan Medical College JCJingjiong ChenShanghai Sixth People's Hospital XTXian-Zhu TangNational Institute of Standards and Technology

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Case series reveals heterogeneous clinical presentations in patients with anti-amphiphysin antibodies, highlighting tumor associations.

Key Points

This study aims to analyze clinical characteristics of anti-amphiphysin-IgG-positive autoimmune syndrome and its association with related syndromes and tumors.
Reported clinical data of four patients with anti-amphiphysin-IgG-positive syndrome.
Conducted a literature review on related cases.
Analyzed coexisting neural antibodies in patients.
Identified four cases of anti-amphiphysin-IgG positivity.
Clinical presentations included myelitis, stiff-person syndrome, and conus medullaris-cauda equina syndrome.
Coexisting antibodies included AQP4-IgG and NMDAR-IgG in some patients.
Associated cancer found in one case was lung cancer.

Cite This Study

Wang et al. (2026) studied this question.

synapsesocial.com/papers/69d1fba0a79560c99a0a1bae https://doi.org/10.3389/fimmu.2026.1782004

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Anti-amphiphysin antibody positive autoimmune syndrome: case series and literature review

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Key Points

Cite This Study

Anti-amphiphysin antibody positive autoimmune syndrome: case series and literature review

Discussion

Member takes

Implication

Key Points

Cite This Study

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