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April 5, 2026JHLT OpenOpen Access

Lung Transplant Outcomes in Recipients Waitlisted for Both Single and Double Lung Transplantation

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Authors

VKVictoria Van KirkUniversity of Southern CaliforniaSGShreya GuhaCalifornia Northstate UniversityAPAjay PrasadUniversity of Southern California

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Implication

Retrospective analysis investigates transplant outcomes in waitlisted patients, suggesting double lung offers lower mortality despite complications.

Key Points

  • The study aims to compare the transplant outcomes of patients waitlisted for single and double lung transplantation.
  • Retrospective analysis of the United Network for Organ Sharing Database.
  • Inclusion of patients waitlisted between December 2017 and February 2023.
  • Exclusion of pediatric lung transplants, multiorgan transplants, and lung retransplants.
  • 52.4% received double lung transplantation, 33.3% received single lung transplantation.
  • Median days on the waitlist were 36 for double lung recipients and 43 for single lung recipients.
  • Higher lung allocation score was observed in double lung group (50.58 vs 44.67, p < 0.001).
  • Double lung recipients faced higher rates of prolonged intubation (33.9% vs 19.9%) and reintubation (19.3% vs 13.0%).
  • Lower post-transplant mortality in double lung group compared to single lung group.

Cite This Study

Kirk et al. (2026) studied this question.

synapsesocial.com/papers/69d1fc28a79560c99a0a1cbbhttps://doi.org/10.1016/j.jhlto.2026.100552
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Native-lung complications following single-lung transplantation for interstitial lung disease: an in-depth analysis2024 · 6 citations
  2. 2OPTN/SRTR 2022 Annual Data Report: Lung2024 · 102 citations
  3. 3Single- vs Double-Lung Transplantation in Patients With Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis Since the Implementation of Lung Allocation Based on Medical Need2015 · 173 citations