Case report reveals effective use of dupilumab for managing atopic dermatitis in trichothiodystrophy.
Trichothiodystrophy (TTD) arises from pathogenic changes in several genes, most of which participate in DNA repair or transcriptional and translational processes. Atopic dermatitis may accompany TTD in a minority of cases. Dupilumab can offer a safe and effective treatment option for severe atopic dermatitis in this population.
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O'Mahony et al. (2026) studied this question.
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