Spray‐dried plasma is comparable to conventional plasma products used in the resuscitation of major hemorrhage: In vitro characterization

Jihae Sohn; Mary‐Anne Fell; Lindsay Gingras; Lisa A. Buckley; Mark A. Popovsky; Andrew P. Cap

doi:10.1111/trf.70211

April 2, 2026Transfusion

Spray‐dried plasma is comparable to conventional plasma products used in the resuscitation of major hemorrhage: In vitro characterization

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Key Points

To compare the characteristics of spray-dried plasma with traditional plasma products for major hemorrhage management.
Conducted in vitro characterization of spray-dried plasma and conventional plasma products.
Evaluated rehydration rates and storage stability at room temperature and refrigerated conditions.
Spray-dried plasma shows rapid rehydration similar to conventional plasma products.
Both plasma types maintain comparable characteristics after 1 and 2 years of storage.

Implication

In vitro analysis compares spray-dried plasma to traditional plasma products, indicating potential clinical application.

Abstract

Spray-dried plasma rehydrates rapidly and has in vitro characteristics comparable to standard-of-care products after storage at room temperature for 1 or 2 years refrigerated. Clinical study of spray-dried plasma is warranted.

Discussion

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Cite This Study

Sohn et al. (2026) studied this question.

synapsesocial.com/papers/69d1fd62a79560c99a0a369f https://doi.org/10.1111/trf.70211

View Full Paper

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Spray‐dried plasma is comparable to conventional plasma products used in the resuscitation of major hemorrhage: In vitro characterization

Key Points

Implication

Abstract

Discussion

Cite This Study

Spray‐dried plasma is comparable to conventional plasma products used in the resuscitation of major hemorrhage: In vitro characterization

Key Points

Implication

Abstract

Discussion

Cite This Study

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