Key result
Non-Hispanic Black race in cervical cancer linked to ~91% greater mortality risk versus Hispanic patients.
Why the study?
Variations in HPV prevalence, tumor genomic alterations, and survival outcomes across population groups remain incompletely characterized.
Observational (n=117,170)
Yes
Effect estimate: 91% worse mortality risk
Absolute Event Rate: 60% vs 76%
p-value: p=<0.0001
Significant population-level variations exist in HPV infection patterns, cervical cancer incidence, somatic mutations, and survival, with non-Hispanic Black patients experiencing the worst survival outcomes.
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May warrant equity efforts for NHB cervical cancer patients; extends evidence of racial disparities in HPV prevalence and survival.
Hussain et al. (2026) conducted an observational in Cervical cancer and HPV infection (n=117,170). Non-Hispanic Black race vs. Hispanic race was evaluated on 5-year overall survival (91% worse mortality risk, p=<0.0001). Non-Hispanic Black race in patients with cervical cancer was associated with a 91% worse mortality risk and lower 5-year overall survival (60%) compared to Hispanic patients (76%, p<0.0001).
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