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April 5, 2026Cancer Research0 citations

Long-Term Exposure to Wildfire Smoke PM2.5 and Older Lung Cancer Patient Survival

Abstract 6251: Long-term exposure to wildfire smoke PM2.5 and survival of older lung cancer patients.

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Authors

MZMin ZhangJWJuan P. WisniveskyMQMinghao Qiu

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Overview

Cohort study investigates wildfire smoke PM2.5 impacts on lung cancer mortality risk in older adults, suggesting implications for clinical care.

Key Points

  • This research aims to evaluate the impact of long-term exposure to wildfire smoke PM2.5 on all-cause mortality among older lung cancer patients.
  • Cohort study using SEER-Medicare database from 2006 to 2019
  • Participants included patients aged 65 and older with a primary lung cancer diagnosis
  • Estimations of exposure based on residential zip codes with a moving average of wildfire smoke PM2.5
  • Each 1-μg/m3 increase in wildfire smoke PM2.5 was linked to a 9.3% increase in mortality risk
  • Wildfire smoke PM2.5 showed a greater mortality risk compared to non-smoke PM2.5 (HR: 1.09 vs. HR: 1.020)
  • Higher risks were noted among women and patients with comorbidities or other lung cancer types (not non-small cell lung cancer)

Cite This Study

Zhang et al. (2026) studied this question.

synapsesocial.com/papers/69d1fdd4a79560c99a0a4176https://doi.org/10.1158/1538-7445.am2026-6251
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