Key result
Post-PVI high-density remapping with guided incremental lesions resulted in comparable long-term recurrence-free survival compared to standard PVI.
Why the study?
Pulmonary vein isolation has acceptable success rates but pulmonary reconnection remains a problem and the role of post-PVI remapping to guide additional lesions is uncertain.
Does post-PVI high-density remapping with guided incremental lesions improve long-term recurrence-free survival in patients undergoing PVI?
Cohort
Does post-PVI high-density remapping with guided incremental lesions improve long-term recurrence-free survival in patients undergoing PVI?
Post-PVI high-density remapping with guided incremental lesions did not significantly improve long-term recurrence-free survival compared to standard PVI.
Answers are grounded in this paper and cite their sources.
Should not yet alter post-PVI ablation practice; leaves open whether voltage remapping reduces recurrence in randomized trials.
Background: Pulmonary vein isolation (PVI) has demonstrated acceptable success rates; however, there is still potential for improvement. Pulmonary reconnection remains the main problem and the role of adjunctive strategies, such as repeat mapping to guide additional lesions to enhance durability of pulmonary vein isolation, remains uncertain. Objective: This study aimed to evaluate the impact of post-PVI high-density remapping with guided incremental lesions on long-term recurrence-free survival. Methods: This study included consecutive patients who underwent PVI between 2015 and 2023. Patients were divided into 2 groups based on whether they received post-PVI high-density remapping. Those in the remapping group with documented areas of incomplete ablation received incremental lesions to achieve complete ablation. The primary endpoint was recurrence-free survival. Results: .03). However, long-term outcomes were comparable between the 2 groups. Conclusion: Postablation mapping effectively identifies and addresses proarrhythmic foci, potentially reducing atrial fibrillation recurrence and improving patient outcomes.
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Rodriguez et al. (2025) conducted a cohort in Atrial fibrillation. Post-PVI high-density remapping with guided incremental lesions vs. No post-PVI high-density remapping was evaluated on recurrence-free survival. Post-PVI high-density remapping with guided incremental lesions resulted in comparable long-term recurrence-free survival compared to standard PVI.
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