Randomized trial reveals that oral FTC-TDF prevents HIV infection in men who have sex with men, indicating that preexposure chemoprophylaxis effectiveness depends on drug adherence.
Oral FTC-TDF provided protection against the acquisition of HIV infection among the subjects. Detectable blood levels strongly correlated with the prophylactic effect. (Funded by the National Institutes of Health and the Bill and Melinda Gates Foundation; ClinicalTrials.gov number, NCT00458393.).
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Grant et al. (2010) studied this question.
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