Eruptive Lentiginosis Within Resolved Psoriasis Plaques: A Case Report and Systematic Review of the Literature

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Key Points

To explore the underlying mechanisms and potential treatments for eruptive lentiginosis associated with resolved psoriasis plaques.
Case report of a patient with eruptive lentiginosis and a history of prothrombin deficiency.
Systematic review of literature on eruptive lentiginosis in relation to psoriasis.
Analysis of potential mediators like UV radiation and cytokines in eruptive lentiginosis development.
Identification of inflammatory cytokines (TNF-α, IL-17, IL-23) as potential mediators of melanocyte proliferation.
Documented persistence of eruptive lentiginosis without treatment, differing from other post-inflammatory pigmentation forms.
Noted partial improvement of eruptive lentiginosis with Q-switched ruby laser treatment.

Case report and systematic review reveal mechanisms and treatment implications for eruptive lentiginosis.

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Kosharek et al. (2026) studied this question.

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